Personalized brain stimulation therapy synchronizes therapeutic stimulation to the individual brain state of patients with neuropsychiatric disorders like depression, OCD, and schizophrenia by targeting the precise phase of brain oscillations at millisecond intervals, using real-time signal processing to analyze brain activity and trigger stimulation at optimal moments, which addresses the limitations of one-fits-all approaches and offers improved treatment outcomes.
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Personalized Brain Therapy for OCD and DepressionAñadido:
We really think that at one point we will be able at Sync-To-Brain to provide >> [music] >> therapy options for neuropsychiatric diseases, diseases like depression, [music] like obsessive-compulsive disorder, like schizophrenia. Many of these disorders are specific brain network [music] disorders where there is a specific region in the brain that is dysfunctional. Brain stimulation therapy that is out there [music] today is a one-fits-all solution and the outcomes are not as good as they could be. Sync-To-Brain commercializes the technology that allows [music] brain stimulation therapy to be synchronized to the individual brain state of the patient.
>> We're trying to target the phase of [music] oscillations. This is an instantaneous state that only lasts a few milliseconds. We need to process every millisecond. That's a special use case that is not addressed by a standard [music] operating systems. And what we have done is to use Simulink real-time programming environment [music] and hardware platform to use the tools that are available in that that MathWorks toolbox to to do all the digital signal processing that that is necessary. We read in brain activity data. We analyze that data and then make a decision at which instant to trigger therapeutic stimulus through a commercially available stimulation system.
The special situation in a startup [music] is that resources are very limited in the beginning. You have your idea, you're trying to get going, but you don't have a lot of people, and you want to test your idea first. [music] And the startup program from MathWorks really helps to get started because prices are not too high, but also you have access to engineers, to [music] people with a lot of knowledge for these tools.
>> We've had a lot of success with regular [music] meetings with experts at MathWorks who helped us review how we were using those tools and be able to just [music] send a quick email, you know, is this the intended behavior? Am I doing it the way that it it's intended? [music] And always getting fast and very helpful feedback from the MathWorks team. This treatment has huge potential and is is is something [music] which can really change how we can treat neurological and psychiatric [music] brain disorders. And if I can contribute with this technology to improve therapy for those patients, then it's [music] something worth working for.
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